Curcumin is the primary bioactive substance in turmeric, and has anti-inflammatory properties and decent evidence for indications from chronic pain to depression. It has poor bioavailability alone, necessitating special formulations to be efficiently absorbed.

Curcumin, a substance in turmeric, may help to reduce inflammation. Several studies suggest that it might ease symptoms of osteoarthritis and rheumatoid arthritis, like pain and inflammation. Other compounds in turmeric might also be medicinal.